The present work aimed to improve thyme plant productivity of herb and volatile oil by using the best treatments of bio-fertilization (biological strains) and complete fertilizer (kristalon) or biomagic as well as complete fertilization [concentrations and number of sprays]. In addition , studying the effects of these treatments on growth, herb yield, volatile oil yield and some chemical constituents as (pigments, carbohydrates, nitrogen, phosphorus and potassium) of thyme under sandy soil and drip irrigation system of North Sinai conditions.The obtained results clear that thyme plants must be fertilized by the interaction treatment between mixture of Azotobacter (A) with Bacillus (B) and biomagic at 7.5 g/L to obtain the highest productivity of herb and volatile oil under sandy soil and drip irrigation system of North Sinai region conditions. In addition, thyme plants must be fertilized with complete fertilizer (kristalon) at 3000 ppm concentration as three sprays to obtain the highest productivity of herb and volatile oil under sandy soil and drip irrigation system of North Sinai region conditions.