Pyrrolizidine and tetrahydroisoquinoline alkaloids from Echium humile

Faculty	Pharmacy	Year:	1996
Type of Publication:	Article	Pages:	225-230
Authors:	ELDAHMY, S, SARG, T, ElShazly, A, Ateya, A, Aziz, EA, Witte, L, Wink, M	DOI:	10.1016/0031-9422(95)00847-0
Journal:	PHYTOCHEMISTRY PERGAMON-ELSEVIER SCIENCE LTD	Volume:	42
Research Area:	Biochemistry \& Molecular Biology; Plant Sciences	ISSN	ISI:A1996UF46700043
Keywords :	Echium humile, Boraginaceae, pyrrolizidine alkaloids, echihumiline, pycnanthine, echihumiline N-oxide, 7- and 9-senecioylretronecine, lycopsamine, 7-acetyl-lycopsamine, tetrahydro-isoquinoline, carnegine
Abstract:	Three new pyrrolizidine alkaloids, echilumiline, pycananthine and echihumiline N-oxide, were isolated from Echium humile and their structures determined by spectroscopic methods. In addition, we record the presence of the known alkaloids, 7-senecioylretronecine, 9-senecioylretronecine, lycopsamine and 7-acetyl-lycopsamine. The tetrahydro-isoquinoline alkaloid, carnegine, was reduced for the first time in the Boraginaceae.
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