Synthesis and reactions of 2-mercaptomethyl-1,3,4-oxadiazolin-5-one

Faculty	Science	Year:	1996
Type of Publication:	Article	Pages:	549-555
Authors:	HAMAD, MM, SAID, SA, ElEkyabi, YM
Journal:	MONATSHEFTE FUR CHEMIE SPRINGER-VERLAG WIEN	Volume:	127
Research Area:	Chemistry	ISSN	ISI:A1996UM73800011
Keywords :	1, 3, 4-oxadiazole, nitrogen nucleophiles, cycloaddition
Abstract:	The title compound (4) was synthesized from thioglycolic acid hydrazide and ethyl chloroformate. The reactions of 4 with aromatic amines, amino derivatives, hydrazine hydrate, hydroxylamine, and formamide were studied. Addition of compound 4 to alpha,beta-unsaturated compounds, i.e. chalcones, maleic anhydride, quinones, and acrylonitrile, was investigated.
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