Heteroannulation of cyclic enaminone and dimedone

Faculty	Science	Year:	1996
Type of Publication:	Article	Pages:	608-610
Authors:	ASSY, MG, AbdEllMotti, FM
Journal:	INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY COUNCIL SCIENTIFIC INDUSTRIAL RESEARCH	Volume:	35
Research Area:	Chemistry	ISSN	ISI:A1996VP09600024
Keywords :	Heteroannulation , cyclic enaminone , dimedone
Abstract:	Enaminone (1) undergo cyclization with benzylidenes (2a-c) to give quinolines (3a-c) which are converted into quinolinopyrimidines (5a-c) by treatment with benzoylisothiocyanate. Cyclocondensation of 1 with benzolisothiocyanate furnishes quinazolone (7). Thioamide 9 have been transformed into isoquinoline (10) and pyrazole (11). The synthesis of phthalazine (12), pyranopyridazine (13) and hydrazone (14) have also been described.
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