Pyrrolizidine alkaloids of Cynoglossum officinale and Cynoglossum amabile (family Boraginaceae)

Faculty Pharmacy Year: 1996
Type of Publication: Article Pages: 415-421
Authors:
SARG, T, ElShazly, A, Ateya, A, Aziz, EA, Witte, L, Wink, M
DOI: 10.1016/0305-1978(96)00035-X
Journal: BIOCHEMICAL SYSTEMATICS AND ECOLOGY PERGAMON-ELSEVIER SCIENCE LTD Volume: 24
Research Area: Biochemistry \& Molecular Biology; Environmental Sciences \& Ecology; Evolutionary Biology ISSN ISI:A1996VR09300006
Keywords : Cynoglossum officinale, Cynoglossum amabile, Boraginaceae, pyrrolizidine alkaloids, capillary GLC, GLC-MS, H-1, C-13 NMR    
Abstract:
Heliosupine, heliosupine N-oxide, 3'-acetylheliosupine, and viridiflorine were isolated and identified on the base of MS, H-1 and C-13 NMR from Cynoglossum officinale. Altogether 14 pyrrolizidine alkaloids were separated and identified by GLC and GLC-MS in the alkaloid extracts from different parts of Cynoglossum officinale. From Cynoglossum amabile five pyrrolizidine alkaloids were recorded: supinine, amabiline, rinderine, echinatine, and 3'-O-acetylechinatine. Copyright (C) 1996.
    
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