Zagazig University Digital Repository
Home
Thesis & Publications
All Contents
Publications
Thesis
Graduation Projects
Research Area
Research Area Reports
Search by Research Area
Universities Thesis
ACADEMIC Links
ACADEMIC RESEARCH
Zagazig University Authors
Africa Research Statistics
Google Scholar
Research Gate
Researcher ID
CrossRef
Synthesis and antihypertensive activity of novel 1-(4-benzyl-1-phthalazinyl)-pyrazolo{[}3,4-d]pyrimidines
Faculty
Pharmacy
Year:
1996
Type of Publication:
Article
Pages:
540-543
Authors:
ELFEKY, SA, ElSamii, ZKA
Journal:
PHARMAZIE GOVI-VERLAG GMBH
Volume:
51
Research Area:
Pharmacology \& Pharmacy; Chemistry
ISSN
ISI:A1996VD42200005
Keywords :
Synthesis , antihypertensive activity , novel 1-(4-benzyl-1-phthalazinyl)-pyrazolo{[}3,4-d]pyrimidines
Abstract:
Convenient Syntheses of derivatives of the pyrazolo{[}3,4-d]pyrimidines from 1-(4-benzyl-1-phthalazinyl)-3-amino-4-cyano-5-methylpyrazole (1) and carbon disulphide, aryl isothiocyanates, nitriles or guanidine are described. Derivatives of compound 1 undergo cyclization to the titled ring system by action of dimethylformamide dimethylacetal or hydrogen sulphide followed by treatment with triethylamine. Some of the new compounds were studied as antihypertensive agents.
Online
PDF
جامعة المنصورة
جامعة الاسكندرية
جامعة القاهرة
جامعة سوهاج
جامعة الفيوم
جامعة بنها
جامعة دمياط
جامعة بورسعيد
جامعة حلوان
جامعة السويس
شراقوة
جامعة المنيا
جامعة دمنهور
جامعة المنوفية
جامعة أسوان
جامعة جنوب الوادى
جامعة قناة السويس
جامعة عين شمس
جامعة أسيوط
جامعة كفر الشيخ
جامعة السادات
جامعة طنطا
جامعة بنى سويف