Purpose – This study aims to investigate the Impact of geopolitical risk (GPR) and economic policy uncertainty (EPU) on corporate cash holding in Egyption companies, it also investigates whether financial constraints affect the relationship between both EPU and GPR and corporate cash holdings. Design/methodology/approach – The researcher relied on a sample of (93) non-financial companies listed in the Egyptian Stock Exchange with a total of (1209) observations during the time series extending from 2011 to 2023, in order to test four research hypotheses through eight statistical models, by using the Ordinary Least Squares (OLS) method, and the Generalized Least Squares (GLS) method. Findings – The results indicated evidence to support the hypothesis of the precautionary (protective) motive to hold cash in the face of costly external financing resulting from geopolitical tensions and economic policy uncertainty. Egyptian firms tend to accumulate cash as a buffer against negative shocks to their cash flows, as holding excess cash is considered a hedge against a turbulent economic environment. On the other hand, since financially constrained firms face higher costs in obtaining external financing, the results indicated that holding cash in these firms is significantly affected by geopolitical and economic uncertainty variables. In addition, firms adjust their cash holdings faster during periods of geopolitical risk and high economic uncertainty mainly to avoid costly external financing.