This study presents the first comprehensive techno-economic assessment of wind-based green hydrogen production across Senegal, a country highly dependent on fossil fuel imports. Using a novel integrated approach combining 30 years of ERA5 reanalysis data (1993–2023), turbine performance modeling and electrolyzer comparison, it fills an important gap for renewable hydrogen development in West Africa. Wind resources were analyzed at multiple altitudes, revealing strong potential in both coastal and northeastern regions, particularly during the dry season, with higher wind speeds at higher turbine heights. Four turbines (Vestas_150, Goldwind_155, Vestas_126 and Nordex_N100) and two electrolyzer types (alkaline and PEM) were evaluated. The alkaline system performed best. Vestas_150 and Goldwind_155 achieved the highest hydrogen yields of 241 and 183 tons/year and CO2 reductions of 2951 and 2241 tons/year, generating carbon credits of 0.118 M$ and 0.089 M$, respectively. Their levelized cost of electricity remained low (0.042 and 0.039 $/kWh), while smaller turbines showed higher costs. Vestas_150 also had the shortest payback period of 2.16 years, making it the most competitive option. Sensitivity analyses showed that longer system lifespans and high-performance turbines significantly reduce the levelized cost of hydrogen. Priority investment zones include Saint-Louis, Matam, Louga and Tambacounda, with levelized cost of hydrogen values as low as 3.4 $/kg.