Magnetic resonance imaging features of post-COVID-19 regional and invasive sino-nasal mucormycosis

Faculty Medicine Year: 2022
Type of Publication: ZU Hosted Pages:
Authors:
Journal: Egyptian Journal of Radiology and Nuclear Medicine Springer Nature Volume:
Keywords : Magnetic resonance imaging features , post-COVID-19 regional    
Abstract:
Sino-nasal mucormycosis is an opportunistic, invasive fungal disease which has shown a rising trend in the setting of COVID-19. The objective of this study is to document and analyze demographic data, clinical presenta‑ tion and MR imaging spectra for early detection and management of post-COVID-19 sino-nasal mucormycosis. Results: Sixty-two cases of sino-nasal mucormycosis were enrolled in this study; their mean age was 50.65±8.25 years, with signifcant female predominance. Nine patients (14.5%) had active COVID-19 and 53 (85.5%) were recent COVID-19 cases. Sixty patients have not received COVID-19 vaccine. The mean duration from the initial COVID-19 laboratory confrmation to the detection of sino-nasal mucormycosis was 25.7+/−4.6 days. Thirty-fve patients (56.5%) were kept in the hospital for COVID management and 4 of them received intensive care unit (ICU) treatment. Twenty-seven patients (43.5%) were treated in home isolation. Corticosteroids were administered in 48 cases (77.4%). Twenty-nine patients (46.8%) had been given oxygen for an average time of 11.2±4.15 days. Diabetes was found in 56 cases (90.3%). The most common clinical symptoms were headache, seen in 52 patients (83.87%). The ethmoid sinus was the most common paranasal sinus involved in our study, seen in 47 cases (75.81%). In 36 cases (58%), multiple sinuses were involved. MRI staging according to the extent of regional involvement. Stage 1 seen in 2 cases (3.23%), stage 2 in 13 cases (20.97%), stage 3 in 35 cases (56.45%) and stage 4 in 12 cases (19.35%). Conclusions: MRI shows a spectrum of fndings in sino-nasal mucormycosis. Imaging plays a major role in staging and assessing the extent of involvement and complications. In light of this, mortality and morbidity can be dramati‑ cally decreased with adequate evaluation and therapy
   
     
 
       

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