Dietary α-sitosterol mitigates titanium dioxide nanoparticle-induced hemato-immunotoxicity, oxidative stress, and gene expression dysregulation in Oreochromis niloticus

Faculty Veterinary Medicine Year: 2025
Type of Publication: ZU Hosted Pages:
Authors:
Walaa Alhuseiny Aldosouky Sliem
Journal: Frontiers in Marine Science Frontiers Volume:
Keywords : Dietary α-sitosterol mitigates titanium dioxide nanoparticle-induced    
Abstract:
Titanium dioxide nanoparticles (TDNPs) are widely used in food industries, agricultural and consumer products, and diagnostic purposes, leading to their potential release into aquatic environments and associated physiological risks to non-target aquatic organisms, particularly fish. α-Sitosterol (STL), a phytosterol, acts by enhancing antioxidant defenses and modulating inflammatory signaling pathways. Hence, this study investigated whether dietary STL can protect Nile tilapia (Oreochromis niloticus) from TDNPs-induced toxicity during a 60-day exposure.
    
     
 
       

Author Related Publications

  • Walaa Alhuseiny Aldosouky Sliem, "Dietary Parsley Seed Mitigates Methomyl-Induced Impaired Growth Performance, Hemato-Immune Suppression, Oxidative Stress, Hepato-Renal Damage, and Pseudomonas aeruginosa Susceptibility in Oreochromis niloticus", MDPI, 2022 More
  • Walaa Alhuseiny Aldosouky Sliem, "Physiological Performance, Antioxidant and Immune Status, Columnaris Resistance, and Growth of Nile Tilapia That Received Alchemilla vulgaris-Supplemented Diets", MDPI, 2022 More
  • Walaa Alhuseiny Aldosouky Sliem, "Study on Argulosis in Koi (Cyprinus Carpio) and some trials for treatment", Zagazig University; Faculty of Veterinary Medicine, 2011 More
  • Walaa Alhuseiny Aldosouky Sliem, "Ameliorative effects of Moringa oleifera seeds and leaves on chlorpyrifosinduced growth retardation, immune suppression, oxidative stress, and DNA damage in Oreochromis niloticus", Elsevier BV, 2019 More
  • Walaa Alhuseiny Aldosouky Sliem, "Effect of hexavalent chromium exposure on the liver and kidney tissues related to the expression of CYP450 and GST genes of Oreochromis niloticus fish: Role of curcumin supplemented diet", Elsevier Inc., 2019 More

Department Related Publications

  • Walaa Mohamed Alhadi Hassan, "دراسة التأثير السمى الجينى لمبيدى الحشائش الراوند أب والاستومب على سمك القرموط النيلى", مجلة الطب البيطرى - جامعة الزقازيق, 2014 More
  • Amany Abdalaziz , "Appraisal of sub-chronic exposure to lambada-cyhalothrin and/or methomyl on the behavior and hepato-renal functioning in Oreochromis niloticus: Supportive role of taurine-supplemented feed", Elseviere, 2022 More
  • Yasmina Mohamed Abdelhakem Elghazaly, "Dietary Parsley Seed Mitigates Methomyl-Induced Impaired Growth Performance, Hemato-Immune Suppression, Oxidative Stress, Hepato-Renal Damage, and Pseudomonas aeruginosa Susceptibility in Oreochromis niloticus", MDPI, 2022 More
  • Taghreed Saber Mohamed Sayed Ahmd, "Thymol alleviates imidacloprid-induced testicular toxicity by modulating oxidative stress and expression of steroidogenesis and apoptosis-related genes in adult male rats", Elsevier Inc, 2021 More
  • Taghreed Saber Mohamed Sayed Ahmd, "Early postmortem biochemical, histological, and immunohistochemical alterations in skeletal muscles of rats exposed to boldenone undecylenate: Forensic implication", Elsevier Inc, 2021 More
Tweet