A broad class of organic compounds known as Schiff bases (SBs) are distinguished by the presence of carbon–nitrogen double bonds (–C=N–). They are generated by condensation processes, usually with the aid of solvents like methanol, between primary amines and aldehydes or ketones. The numerous biological actions of these substances, including their antibacterial, antifungal, antiviral, anti-inflammatory, and antioxidant qualities, have attracted a lot of research. Schiff bases are produced when primary amines react with aldehydes or ketones. They have antioxidants, antiviral, antibacterial, antifungal, and anti-inflammatory properties. In coordination chemistry, Schiff bases play a crucial role by creating stable metal complexes with different metal ions. Pharmaceuticals, agrochemicals, dyes, analytical chemistry, catalysis, energy storage, environmental applications, chemo-sensing, bio-sensing, and biomedical applications are just a few of the sectors that use Schiff bases. Because Schiff bases may form stable complexes with metal ions, they are essential for both organic and inorganic chemistry. Schiff bases with possible antiviral, antifungal, and antibacterial effects have been the subject of recent research. To improve knowledge of their synthesis procedures, synthetic schemes are developed.