A promising selective platform based on molecularly imprinted polymer@carbon dots (MIP@CDs) was fabricated for the electrochemical detection of oxomemazine (OXO) using square voltammetry technique. MIP@CDs were initially synthesized via thermal polymerization of a complexing monomer (acrylamide-OXO) with ethylene glycol dimethacrylate (crosslinker) in the presence of CDs. The synthesized polymeric particles were investigated using different techniques, including FT-IR, SEM, AFM, BET, and elemental mapping. MIP@CDs were dropped onto the glassy carbon electrode, dried under an infrared lamp, and subsequently characterized electrochemi cally using EIS and CV. The synthesized sensor exhibited a linear response ranging from 2.9 × 10 9 10 3 mol L 1 with a low limit of detection (9.5 × 10 10 mol L 1 to 4.1 × ). Furthermore, it showed good stability (five weeks), excellent selectivity (imprinting factor = 16.3), good reproducibility (RSD = 2.8 %), and repeatability (RSD = 2.1 %). Finally, under optimum conditions, the imprinted sensor was successfully applied to detect OXO in human blood, urine, and syrup samples with excellent recovery (98.25 % – 100.00 %).