Synthesis of Bis-thiazoles Tethered 1,4-Dihydropyridine and Pyridine Linkers via Simple Oxidation and their Molecular Docking as VEGFR-TK Inhibitors

Faculty Science Year: 2024
Type of Publication: ZU Hosted Pages:
Authors:
Journal: Current Medicinal Chemistry Bentham Science Volume:
Keywords : Synthesis , Bis-thiazoles Tethered 1,4-Dihydropyridine , Pyridine Linkers    
Abstract:
In this study, a neoteric and expedient oxidation method is applied for a variety of Hantzsch 1,4-dihydropyridine derivatives such as 1,4-dihydro-2,6-dimethyl-3,5-diacetylpyridine, 3,5-bis-hydrazono--2,6-dimethyl-1,4-dihydropyridine, and 3,5-bis-thiazoly-2,6-dimethyl-1,4-dihydro pyridines.
    
     
 
       

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