This experiment was applied to evaluate the impacts of novel amino acid profile based on high lysine (Lys) levels and adequate crude protein (CP) with inclusion of sunflower meal on growth, economic efficiency and characteristics of broiler. Three hundred day- old broiler chicks (ROSS 308) were used and classified into six treatments (T1 to T6) in complete random design. There were five replicates of each treatment, each containing 10 chicks. Sunflower meal was included at 5% in all groups except the control (T1). T1 and T2 received diets with the recommended lysine level (100%), while T3 to T6 had increased lysine levels (105%, 110%, 115%, and 120%, respectively). The amino acid profile adjusted according to lysine levels. The results revealed significant improvements in overall performance, BWG and BW increased (P < 0.05) significantly from T1 to T6. The highest weight was observed in T6. Feed intake also increased significantly (P < 0.05) across treatments, while there were no significant variations in FCR between T2, T3, and T4 in comparison the control. T6 exhibited the best feed efficiency. Additionally, gizzard%, liver%, abdominal fat%, and intestine% increased significantly, with T6 showing the highest values. Economic analysis showed that despite higher costs, T6 offered the best economic efficiency. Overall, the study suggested that a high lysine profile with sunflower meal inclusion improved broiler growth performance, enhanced feed efficiency, and offered economic benefits, made it a viable strategy for poultry production.