Counterproductive work behaviors are one of the most important challenges facing organizations in recent times due to the increasing severity of change in the work environment. It generates many negative outcomes at both individual and organizational levels، among which is job burnout. Accordingly، this study aimed to explain the impact of counterproductive work behaviors on job burnout among employees working in general administrative departments at Zagazig University. Usingsurvey، the primary data were collected from a stratified random sample of 300employees working in general administrative departments at Zagazig University. Using the multiple regression analysis method، hypotheses were tested. Using Mann Whitney and Kruskal-Waals test، the results showed that there were significant differences between the dimensions of counterproductive work behaviors on the one hand، and the dimensions of job burnout on the other hand among employees working in general administrative departments، which is due to a number of demographic variables such as gender، age، and occupational degree. Results showed that there is a significant difference in relative importance of the dimensions of counterproductive work behaviors in the development of each of the dimensions of occupational burnout. In addition، there is a positive significant relationship between production deviation، sabotage، withdrawal، and theft، and each of the dimensions of job burnout among employees working in general administrative department at Zagazig University.Results were discussed and fruitful insights have been communicated to managers. Limitations and proposals for future research were suggested.