Agricultural water management is a key factor for sustainable production in semi-arid and arid regions. Precise irrigation is a main strategy for the agricultural water management, where using quick models for irrigation scheduling is an effective way for increasing water use efficiency by crops. This study compared the effectiveness of two irrigation scheduling techniques i.e., ETC values calculated by FAO approach and Crop-R method on potato crop (Solanum tuberosum sp.) grown in sandy soil during the season 2019/2020. Results showed that Crop-R method was more effective than the FAO method in increasing water use efficiency (WUE) by 24%, through maximizing the tuber yield by 3.3% and the applied irrigation water by 7.1%. Moreover, the number of irrigation events decreased from 57 in FAO method to 53 in Crop-R method, which means less energy consumption as well as less CO2 emissions. It is worth mentioning that the Crop-R method saved 675 m3 ha-1 of the irrigation water as compared to the other method. These results support the efforts of agriculture sustainability and water saving in semi-arid and arid regions through irrigation scheduling by the Crop-R method due to its positive effect on crop yield and WUE.