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Non-variceal Causes and Outcome of Acute Upper Gastro intestinal Bleeding among Cirrhotic Patients in Tropical Medicine Intensive Care Unit
Faculty
Medicine
Year:
2019
Type of Publication:
ZU Hosted
Pages:
270-279
Authors:
Gehan Ahmed Shawky Abdallah
Staff Zu Site
Abstract In Staff Site
Journal:
Afro-Egyptian Journal of Infectious and Endemic Diseases (AJIED) Zagazig University
Volume:
4
Keywords :
Non-variceal Causes , Outcome , Acute Upper Gastro intestinal
Abstract:
Background and aim of the work: non variceal bleeding is less common than variceal bleeding among cirrhotic patients; hence there are fewer studies that pay attention to its causes and outcomes. The aim of this study is to shed light on the causes of acute non-variceal bleeding in cirrhotic patients and the outcome of acute upper gastrointestinal bleeding in those patients. Patients and Methods: this cross sectional study included 179 patients, they were allocated into two groups according to the source of bleeding; group I: included 104 patients with variceal bleeding and group II: included 75 patients with non-variceal bleeding. Results: The frequency of non-variceal bleeding was 41.9%. The mean period of intensive care unit stay was 5.03 ± 2.65 days ranging between 1and 17 days. The overall rate of early rebleeding was 3.7% and the mortality rate in intensive care unit was 4.5%. The most common cause of non variceal bleeding is ulceration (24%), followed by portal hypertensive gastropathy (17.3%), and in 24% of cases the cause of bleeding was obscure. Mortality is significantly correlated to white blood cells count (r=0.2 p=0.002), Child’s grade and score (r=0.217 p=0.003 and r= 0.16 p=0.03 successively) as well as Glasgow-Blachford score (r=0.18 p=0.01). Conclusion: The frequency of non variceal bleeding among cirrhotic patients admitted with acute upper gastrointestinal bleeding bleeding is 41.9%. The mortality rate in those patients is 4.5%. The degree of deterioration of liver functions and the severity of initial bleeding episode were the most important predictors of mortality.
Author Related Publications
Gehan Ahmed Shawky Abdallah, "تاثير حركية المرئ الغير مؤثرة في الارتجاع المعدي المتأكلوالغير متأكل", لايوجد, 1900
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Gehan Ahmed Shawky Abdallah, "دراسةالديناميكية الدموية للوريد البابي وامكانية حدوث دوالي المعدة بعد عملية استئصال الطحال", لايوجد, 1900
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Gehan Ahmed Shawky Abdallah, "Prognostic Value of Doppler Perfusion Index in Early Colorectal Cancer for Adjuvant Chemotherapy", منشور بمجلة بيولوجيا السرطان, 2015
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Gehan Ahmed Shawky Abdallah, "Urinary Neutrophil Gelatinase-Associated Lipocalin as Predictor for Development of Hepatorenal Syndrome in Patients with Hepatic Cirrhosis", منشور بالمجلة الافريقية المصرية للأمراض المعدية والمتوطنة, 2014
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Gehan Ahmed Shawky Abdallah, "Circulating Resistin and Visfatin Levels in Patients with Inflammatory Bowel Disease as Predictors of Treatment Response", منشور بالمجلة الافريقية المصرية للأمراض المعدية والمتوطنة, 2014
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Department Related Publications
Ahmed Attia Abdelmoeti Abdulbaky, "How Frequent Is Sleep-Disordered Breathing Among Egyptian Cirrhotic Adults", Termedia Publishing House, 2020
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Ahmed Attia Abdelmoeti Abdulbaky, "Interleukin-6 and C-reactive Protein/Albumin Ratio As Predictors of COVID-19 Severity and Mortality", Wolters Kluwer – Medknow, 2021
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Ahmed Attia Abdelmoeti Abdulbaky, "The Effects of Sofosbuvir-Based Treatment of Hepatitis C Virus On Patients With Chronic Obstructive Pulmonary Disease", Wolters Kluwer – Medknow, 2020
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Ahmed Attia Abdelmoeti Abdulbaky, "Effect of rifaximin in the prevention of acute kidney injury and hepatorenal syndrome type II in Egyptian HCV cirrhotic patients", Zagazig Faculty of Medicine, 2021
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Ahmed Attia Abdelmoeti Abdulbaky, "Evaluation of INR Elevation in Cirrhotic Patients as a Risk Factor for Esophageal Variceal Bleeding", zagazig universty , faculty of medicine, 2017
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