The study aimed to uncover the relationship between adolescents' personality traits and their self-presentation strategies on social media platforms, while analyzing the mediating role of self-esteem and life satisfaction in enhancing this relationship. The study was conducted on an available sample of social media users aged 18–21 years (late adolescence), with a total sample size of 427 individuals. The results confirmed that personality traits significantly influence adolescents' self-presentation strategies on social media platforms, as these strategies reflect individuals’ attempts to manage their self-image. Adolescents high in openness to experience tend to use a variety of strategies such as ingratiation, damage control, manipulation, and self-promotion. Adolescents high in conscientiousness use these strategies to maintain a positive image. Extraverted adolescents, being social and active, use self-presentation strategies to enhance their presence and influence, while agreeable adolescents seek to maintain positive relationships and a good image through cooperation and empathy. On the other hand, adolescents high in neuroticism are more likely to use ingratiation, damage control, and manipulation strategies, but not self-promotion, due to anxiety and emotional instability. The findings also revealed that the tendency for social comparison has a relative, yet not the strongest, impact on the relationship between personality traits and self-presentation strategies. Moreover, self-esteem plays a significant role in strengthening this relationship, indicating that adolescents with high self-esteem tend to use self-presentation strategies more effectively. Additionally, life satisfaction enhances the relationship between personality traits and self-presentation strategies, reflecting that adolescents who are satisfied with their lives tend to engage in positive self-presentation strategies.