There is a correlative relationship between mediatization and social interaction. Communication scholars have paid attention to this relationship. We argue that mediatization involves the incorporation of various patterns of interaction among users of social media platforms. We used two theoretical approaches, namely mediatization and symbolic interaction. We surveyed a purposive sample that we selected according to certain criteria. Regression analysis revealed the correlative relationship between the dimensions of mediatization over social media platforms and the patterns of symbolic interaction among users.