The current study aimed to investigate the infection rate and diversity of enteric parasites in domestic turkeys (Meleagris Gallopavo) in different localities of Egypt. One hundred and thirty intestines were collected from slaughtered turkeys; 97 from Zagazig City in Sharkia Province and 33 from El-Salam Abattoir in Cairo Province. The total prevalence of parasitic infection reached 49.23%. The rates were 62.89% and 9.09% in examined samples from Zagazig City and El-Salam Abattoir. Nematoda infections included Heterakis gallinarum (34.6%), Capillaria species (13.08%), Trichostrongylus tenuis (5.38%) and Strongyloides avium (0.77%). Protozoan infections included Eimeria species (18.46%); Balantidium species (0.77%) and Cryptosporidium species (3.08%). In wet season, the infection rate (59.02%) was higher than in dry one (40.58%). In wet season, the percentages of single, double, triple and fifth infection reached 18.03%, 27.87%, 11.48% and 1.64%, respectively; but in dry season, the percentage of single, double and triple infection reached 30.43%, 5.8% and 4.35%, respectively. A significant increase of H. gallinarum was observed all over the year, while Eimeria species infection rate was significantly higher in the wet season. In relation to seasonal variations of co-infections, double infection type recorded significant higher values both in wet and dry seasons than the other infection types. The current study recommends the urgent need to use advanced and improved methods of animal care and management, as well as testing of new antiparasitic agents for control of such parasites, whether on farms or in home turkey housing system, to reduce the risks of increasing parasitic infection rates