Introduction: Meningioma is the main prevalent kind of primary brain tumor, which affects a variety of life aspects, including the social, psychological, and physiological ones. Even after meningioma patients have had surgery, some of them continue to suffer from aftereffects like headaches, limited mobility, activity interruption, and visual abnormalities (Ganefianty& Yona., 2019). Meningiomas represent the predominant category of intracranial tumors in adults and arise from the arachnoid cells of the middle layer of meninges. The World Health Organization (WHO) categorizes them into three categories: benign (grade I), atypical (grade II), or malignant/anaplastic (grade III), despite they typically exhibit slow growth and behave benignly in most cases (Salles et al., 2021). A professional neurological assessment indicated that nurses are essential for taking care of patients undergoing various stages of treatment for brain tumors and are vital to the patient's final outcome. Additionally, they are performing a crucial part in these patients' health education. The nurses must be fully informed of patients' needs to provide optimal nursing care and education that improves the patient's well-being (Gaber et al., 2016). Aim of the study: To assess the effect of Nursing Educational Strategies regarding Complications Post Meningioma on Nurses Knowledge and Practices Hypothesis Nursing educational strategies regarding complications post meningioma significantly influence nurses’ knowledge and practices. Research Design: A quasi-experimental research design was utilized to conduct the study. Study setting: This investigation was conducted in the Department of Neurosurgery at the Surgery Hospital at Zagazig University. The Neurosurgery department resides on the sixth floor. It comprises two sections: a female section and a male section. Each section includes 9 rooms.. Study Sample: A purposive sample of The sample consisted of the entire 35 nurses employed at the Surgery hospital in Zagazig. . 1 Tools for data collection: Tool One: Self-Administered Knowledge Questionnaire This tool was developed by researchers utilizing contemporary national and international research and literature. It includes two parts:  Part 1: Demographic Data Sheet: This section collects participants' demographic information, containing age, marital status, gender, residence, educational level, and income.  Part 2: Nurse Knowledge Questionnaire: This section includes 95 items covering various aspects of meningioma, such as its definition, causes, manifestations, complications, and nursing strategies. Tool Two: observational Nurses’ Practices Checklist The tool was designed by researchers following the studying of relevant articles and research to evaluate nurses' strategies regarding complications may occur for patients after meningioma surgery. It consists of 20 steps including vital signs, pain assessment, neurological assessment, visual assessment, complications assessment, Communication and Cognitive Function assessment, and Disability assessment. Pilot study: An initial trial was executed in September 2022 to assess the practicality and suitability of the research methods. It included 10% of the sample, comprising 4 nurses. Furthermore, it offered an estimation of the duration necessary to finalize the tools. Field work Assessment phase In this phase, Assessment of nurse's knowledge, and practices will be done using the first study tool: Researcher started data collection by distributing knowledge questionnaire to collect data about nurses’ characteristics and their knowledge about nursing strategies regarding complications post meningioma. Data was collected in the surgery hospital in the presence of the researcher to provide necessary explanations. Data was collected 3 days per week. Observational checklist were conducted for nurses practice using tool two was used to collect data about practice about nursing strategies regarding complications post meningioma. Data was collected by the researcher directly to the nurses. Data was collected during the morning and afternoon shifts. Planning Phase The investigator studied both national and international literature related to this research, utilizing textbooks, papers, and scientific publications. The intended research setting was assessed on the basis of the nurses at Zagazig surgery hospital. Booklet was developed. Nursing educational strategies was planned. The Nursing strategies aims to appraise the role of nurses in nursing care of patients with meningioma and complications post meningioma designed will be presented in Arabic language. It will be conducted in four sessions. Implementation Phase Five groups of nurses were formed. Every group consisted of 7 nurses. Every group attended 2 sessions for assessment, 2 educational sessions, and 3 practical sessions. Each session lasting 30 to 45minutes. Each nurse in the study sample received a printout of the designed nursing strategies booklet which comprised nursing care activities. The researchers teach each subgroup in the same manner using the same teaching methods and materials including posters, pictures and educational videos. At the beginning of each session, an orientation to 1 the session objective took place. Teaching aids included posters, pictures and educational videos. Introductory sessions before the implementation of the nursing strategies will be done. This session aimed to clarify the aim of nursing strategies. The first session included the aim of the meeting and orientates nurses concerning the nursing strategies. The second and third sessions included: Introduction, simple note on the definition of meningioma, signs and symptoms, and treatment. The fourth session included: prevention, nursing intervention and complications. This was followed by three practical sessions that included applied nursing strategies covering critical practices such as measurement vital signs, pain assessment for patients, neurological assessment for patients, visual assessment, Complications may occur post meningioma, patients' communication and cognitive function assessment, and disability. The researcher used covert observation for nurses . Evaluation phase: During this stage, evaluating the effectiveness of the nursing strategies will be done using knowledge, and practices questionnaire after implementation of the nursing strategies. All over the time of sessions application consolidation of the program was done directly to assess to which extent the participants remember the knowledge and apply the management practices with the target nurses. Post intervention: After completing the nursing educational strategies. Researchers redistributed the same questionnaires again for all the nurses to assess the impact of nursing strategies implementation and to ensure their understanding. The post-test was conducted a month later using the same data collection instruments. Results: There was a revealed that before the nursing program; only 22.5 % of the surveyed nurses possessed a good overall knowledge, however after the nursing strategies intervention; good total knowledge score increased to 62.9%. Before nursing strategies intervention, 68.6% of the surveyed nurses exhibited inadequate practice, however after nursing strategies intervention, satisfactory practice score increased to 74.3. Conclusion: The investigation findings disclosed that the nursing program positively affected and improved nurses' knowledge, and practice related to the nursing strategies for managing complications after meningioma surgery. The nurses who received the nursing strategies had a better level of knowledge and practices than before implementing the nursing strategies. Recommendation: The following recommendations are proposed based on the outcomes of the present research: - Replication of this investigation on a larger scale across several hospitals. - Providing continuous professional training for working nurses about nursing strategies for patients having meningioma.