The ongoing research employs both the neutrosophic set and the Decision Making and Evaluation Method (DEMATEL) to analyze and determine the factors influencing supplier selection within the realm of Supply Chain Management (SCM). Recognized as a proactive strategy for enhancing performance and securing competitive advantages, DEMATEL guides this investigation. The study utilizes neutrosophic set Theory to refine overall assessments, introducing a novel scale to distinctly represent each value. Through a practical case study focusing on selecting the optimal supplier for a distribution company, the proposed methodology's application is illustrated. The research framework integrates a neutrosophic DEMATEL approach for data collection, incorporating surveys among experts and interviews with professionals in management, procurement, and production. In addressing application-oriented challenges characterized by multiple criteria marked by ambiguity and varying degrees of accuracy, Smarandache introduced Treesoft sets an extension of hypersoft sets to effectively navigate through ambiguous and imprecise options.