This study presents an analysis of consumer opinions on waste medicine management. The study explores consumers' concerns, preferences, and suggestions regarding correctly disposing unused or expired medications. The analysis shows the key points that emerged from consumer opinions, including environmental impact, public health and safety, accessibility and affordability, education and awareness, pharmaceutical industry responsibility, convenience and ease of disposal, privacy and confidentiality, community engagement, alternatives to disposal, extended producer responsibility, international collaboration, technology solutions, environmental stewardship, and government regulation and support. This study shows the importance of understanding consumer perspectives in developing effective waste medicine management strategies prioritizing environmental sustainability, public health, and consumer satisfaction. We used the multi-criteria decision-making (MCDM) methodology to deal with these criteria. We gathered 15 criteria concerned with waste medicine management. We used the DEMATEL method to show the criteria weights and relationships between criteria. The DEMATEL method is integrated with the single-valued neutrosophic set to deal with uncertain data. The results show the environmental impact has the most significant weight.