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Implication of endoplasmic reticulum stress and mitochondrial perturbations in remote liver injury after renal ischemia/reperfusion in rats: potential protective role of azilsartan
Faculty
Pharmacy
Year:
2024
Type of Publication:
ZU Hosted
Pages:
Authors:
Israa Mohamed Nagib Mohamed Zakarya
Staff Zu Site
Abstract In Staff Site
Journal:
Redox Report Taylor & Francis
Volume:
Keywords :
Implication , endoplasmic reticulum stress , mitochondrial perturbations
Abstract:
The study uncovered the involvement of mitochondrial perturbations, ER stress and apoptosis in liver injury following renal I/R, and suggested AZL as a preconditioning strategy to ameliorate remote liver injury in patients susceptible to renal I/R after adequate clinical testing.
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Israa Mohamed Nagib Mohamed Zakarya, "A novel approach to repositioning memantine for metabolic syndrome-induced steatohepatitis: Modulation of hepatic autophagy, inflammation, and fibrosis", Elsevier Inc., 2023
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Rana Gamal Mohamed Abdallah, "Pachymic acid attenuated doxorubicin-induced heart failure by suppressing miR-24 and preserving cardiac junctophilin-2 in rats.", MDPI, 2021
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