Journal: |
BMJ Paediatrics Open
BMJ (British Medical Journal) Group and covers a wide range of topics in paediatric medicine, public health, and global child health.
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Volume: |
6;8(1):e003030
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Abstract: |
Mpox (formerly monkeypox) is a viral zoonotic disease caused by the mpox virus (MPXV), which is part of the same family as the smallpox virus.1 Although milder than smallpox, mpox can still lead to severe health issues, particularly in vulnerable individuals. It primarily transmits through close physical contact with an infected person, bodily fluids or contaminated surfaces.1 Initially, mpox presents with fever, headache, myalgia and fatigue, often followed by lymphadenopathy—a hallmark differentiating it from smallpox. Within a few days, a distinctive rash emerges, progressing from flat lesions to fluid-filled blisters and scabs (figure 1).2 These lesions commonly appear on the face, hands, feet and genital regions and usually last up to 4 weeks. While most cases resolve without treatment, complications can arise, especially for those immunosuppressed, potentially leading to secondary bacterial infections or, in severe cases, even to encephalitis and death.
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