Maize (Zea mays L.) is highly sensitve to salt stress, which poses a threat to its producton, especially with predicted increases in salinity due to climate change. Enhancing salt tolerance in maize is critcal to mitgatng these adverse effects, sustaining its producton, and ensuring global food security. This study aimed to evaluate the effects of exogenously applied lipoic acid or Si, alone or in integraton with soil applicaton of vermicomposttea on physio-biochemical components, antoxidant defense systems, growth, and yield of maize plants exposed to salt stress. The applicaton of vermicompost-tea was carried out as a soil treatment incorporated into irrigaton water at a concentraton of 200 L ha-1, and administered in three equal doses in irrigaton water within the last 10 min of drip irrigaton. Silicon was applied at a rate of 6 mM using potassium silicate and lipoic acid was applied at 0.1 mM. Silicon and lipoic acid were applied three tmes at 25, 40, and 55 d afer plantng. The results indicated that the integratve applicaton of soil-based vermicompost-tea with exogenously applied Si or lipoic acid signifcantly enhanced all studied parameters. Specifcally, the combinaton of Si with vermicomposttea exhibited the highest improvement percentage compared to untreated control in chlorophyll a (60.3%), chlorophyll b (72.7%), carotenoids (69.9%), net photosynthetc rate (111%), transpiraton rate (134%), stomatal conductance (129.5%), relatve water content (28.4%), membrane stability index (44.3%), N (33.4%), P (71.9%), K (39.7%), Ca (89.9%), K/Na (81.2%), total soluble sugars (63.7%), proline (60.1%), ascorbate (44.4%), glutathione (83.5%), and α-tocopherol (72.1%). These positve effects were reflected in enhancing yield traits under salt-affected soil conditons by enhancing plant height (25.1%), number of grains per row (43.3%), number of rows per ear (26.7%), 1000-grain weight (25.9%), grain yield (45.4%), and biological yield (42.8%) compared to untreated control.