Background: Educational programs for pregnant women delivered by dentists, and midwives would prevent oral disorders in mothers and also impacting the dental health of offspring. Aim of the study: The main aim of this study is to evaluate the effect of antenatal dental health education program on pregnancy outcomes for Egyptian primigravidas women. Subjects and Methods: Research design: A prospective interventional case control research design was conducted. Subjects: 108 pregnant women who met the inclusion criteria. The sample size was two equal groups and divided into two groups (case and control). Setting: The study was conducted at the prenatal clinic at Zagazig University Hospital. Tools of data collection: The following four tools were used to achieve the study's purpose: a structured interview questionnaire; a scale for assessing knowledge, practice, and attitude; and an outcome checklist for tracking mother and baby outcomes throughout labor. In addition, prenatal education classes were hold to enhance the pregnancy outcomes. Results: According to the study's findings, women who participated in the dental education program had statistically significant positive knowledge, practices and attitudes compared to those in the control group. In the case group, pregnancy outcomes were good and improved after attending dental health program than in control group. Conclusion: Designing and implementing an educational program on antenatal oral health had a significant effect on improving pregnancy outcomes. Recommendation: Awareness educational program about dental care associated to pregnancy was necessary to be recommended.