Abstract Background: Intracorporeal Anastomosis (IA) was found to be an alternative surgical approach which decreases Extracorporeal Anastomosis (EA), related technical problems. Recent studies have compared surgical and techniqual findings of laparoscopic right colectomy with EA or IA, but little information were known about outcomes of performing either laparoscopic left colectomy. Aim of the study was to compare between EA and IA in laparoscopic management of left sided CRC. Material and Methods: we performed a retrospective data analysis of 60 left sided CRC patients of whom we treated 38 (63%) patients by IA, and treated 22 (37%) patients by EA. Results: We found that operative time was shorter (p=0.006), abdominal incision was smaller (p=0.002), postoperative complications were less (p=0.049), in the AI group than that in the EA group. Days spent until occurrence of first flatus in the IA were less than in the EA group (p= 0.049). We found no significant differences between both groups regarding incidence of tumor recurrence, disease free survival rate and overall survival rate. Conclusion: performing a total laparoscopic assisted colectomy with IA for management of left-side cancer colon is technically safe, feasible, has better cosmetic results and faster recovery that EA. Additionally we did not find significant differences between IA and EA in recurrence of the disease, PFS or OS rates.