Approximately 75% of newly emerging infectious human illnesses are zoonotic (originating mainly from animals). All camel-raising countries, where camel meat is of popular consumption, are susceptible to camel zoonotic illnesses. The goal of the current study was to evaluate the microbiological safety and the associated risk factors of increasing microbial prevalence with the antibiogram status of the examined camel meat at the Elbasatien abattoir, which is the oldest and biggest abattoir in Cairo governorate of Egypt. Three zoonotic foodborne pathogens, including Salmonella spp., Staphylococcus aureus, and Escherichia coli, were successfully isolated with prevalence rates of 8% (8/100), 24% (24/100), and 14% (14/100) in the camel meat samples under examination.