The ameliorative role of Aloe vera-loaded chitosan nanoparticles on Staphylococcus aureus induced acute lung injury: Targeting TLR/NF-κB signaling pathways

Faculty Veterinary Medicine Year: 2024
Type of Publication: ZU Hosted Pages:
Authors:
Iman Bushra Abdel Fattah AbdelMeguid
Journal: Open Veterinary Journal Faculty of Veterinary Medicine University of Tripoli, Libya Volume:
Keywords : , ameliorative role , Aloe vera-loaded chitosan nanoparticles , Staphylococcus    
Abstract:
Acute lung injury (ALI) is a severe condition distinguished by inflammation and impaired gas exchange in the lungs. Staphylococcus aureus, a common bacterium, can cause ALI through its virulence factors. Aloe vera is a medicinal plant that has been traditionally used to treat a variety of illnesses due to its anti-inflammatory properties. Chitosan nanoparticles are biocompatible and totally biodegradable materials that have shown potential in drug delivery systems. Aim: To explore the antibacterial activity of Aloe vera-loaded chitosan nanoparticles (AV-CS-NPs) against S. aureus in vitro and in vivo with advanced techniques.
    
     
 
       

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