The current research was conducted to study the use of thermal and non-thermal processing techniques in the sterilization of broiler chicken manure through different periods of exposure. The sterilization process was studied using various thermal processing techniques (sun drying and electric drying) and non-thermal processing techniques (ultraviolet) for exposure times of 1 to 6 hours, as well as re-exposing previously sun-dried and electric-dried manure to UV-C for exposure times of 5, 10, 15, 30, and 60 minutes. The sterilization process was studied based on microbial count, sterilization efficiency, specific energy, and sterilization cost. Findings clarified that sterilizing chicken manure through sun drying is ineffective. Sun drying for 6 hours and subsequently exposure to a UV-C intensity of 1960 µW/cm2 for 5 minutes resulted in a sterilization efficiency of 100%, the lowest specific energy of 0.163 kW.h/kg, and a sterilization cost of 0.228 LE/kg compared to other treatments. Chicken manure can be sterilized using electric drying for up to 5 hours at a specific energy of 58.88 kW.h/kg and a sterilization cost of 82.43 LE/kg. While using electric drying for 2 hours followed by 60 minutes of exposure to a UV-C intensity of 1960 µW/cm2, the manure was sterilized with a specific energy of 25.51 kW.h/kg and a sterilization cost of 35.71 LE/kg. Exposing manure to 1470 µW/cm2 UV-C intensity for 6 hours achieved 100% sterilization efficiency, 8.80 kW.h/kg specific energy, and 12.31 LE/kg sterilization cost. In conclusion, using UV-C is an energy-saving and economical processing technique for sterilizing chicken manure