Bioclimatic architecture is a sustainable design approach that aims to create buildings that put local climate characteristics into consideration and utilize the natural environment to achieve thermal comfort and reduce energy consumption. Among the various strategies used in bioclimatic architecture, natural ventilation stands out as a cost-effective and eco-friendly method that allows for the flow of air through buildings to provide cooling and improve indoor air quality without relying on mechanical systems. With the growing concerns surrounding climate change and sustainable development, the use of natural ventilation techniques is becoming increasingly vital in buildings design. This paper investigates the importance of natural ventilation as one of the bioclimatic architecture strategies for sustainable building design in hot-arid regions characterized by extreme weather conditions, by providing an overview of the various natural ventilation strategies, including single-sided, double-sided, wind-induced, and stack ventilation and identifies the key factors affecting air movement to enhance thermal comfort and indoor air quality inside spaces. The research findings reveal a set of design guidelines that can be implemented to optimize natural ventilation in hot-arid regions. These guidelines cover building orientation, form, vegetation, and the design of openings and natural ventilation strategies that are most suitable for this climate.