| Journal: |
Zagazig university Medical Journal [ZUMJ]
كلية الطب البشرى جامعه الزقازيق
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| Abstract: |
Background: When it comes to pediatric cancer, nutrition could
have a role in nearly every aspect of cancer control for supportive
care, treatment, and recovery. The purpose of this work was to
improve the nutritional status of pediatric patients with cancer
and to evaluate the impact of nutritional counseling and support
among these children.
Methods: This interventional study was carried out on 54
children; they were categorized into two groups (27 in each
group): the interventional group (group 1) that included patients
who had cancer and undergone chemotherapy with complete
nutritional intervention, and the nonintervention group (group 2)
that included patients who had cancer and undergone the
chemotherapy and refuse to complete nutrition intervention. All
patients were subjected to nutritional status and anthropometric
assessment at diagnosis and during treatment, to detect clinical
outcome. Biochemical assessment was done for all patients,
including CBC. direct bilirubin, ALT and AST, albumin and prealbumin, creatinine, and electrolyte test (Ph, Mg, K+
, and Na+
).
Results: Statistically significant increases were revealed in the
degree of malnutrition among the group 2 compared to the group
1 on the 30th, 60th day, and 90th day of follow-up (p<0.05), also
statistically significant increases were revealed in the visits of
dietitian and administration of nutritional supplements in cases of
the interventional group when compared to group 2 during
different times of treatment and follow up (p=0.01, 0.006
respectively). Statistically significant decreases were found in the
mean Hb, HT, and creatinine (p=0.02, 0.01, and <0.001,
respectively) and statistically significant increases in direct
bilirubin at the 45th day of follow-up among the nonintervention
group compared to the interventional group (p<0.001).
Conclusion: Nutritional intervention could have a positive effect
on anthropometric measures, quality of life, biochemical analysis
and hematological findings at different times of follow-up among
studied children with cancer
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