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Detection of Subclinical Cardiac Dysfunction in Healthy Medical Workers with Vitamin D Deficiency
Faculty
Medicine
Year:
2023
Type of Publication:
ZU Hosted
Pages:
Authors:
Moataz Abdel Moneim Mohammed Qott
Staff Zu Site
Abstract In Staff Site
Journal:
zagazig university medical journal zagazig university medical journal
Volume:
Keywords :
Detection , Subclinical Cardiac Dysfunction , Healthy Medical
Abstract:
ABSTRACT Background: Vitamin D is a necessary hormone in many tissues including cardiac myocytes. The autocrine and paracrine regulation of cellular growth differentiation and function in several organs depends on it through preventing the activation of the heart’s renin-angiotensin system and natriuretic peptides vitamin D regulates calcium Flux, extracellular matrix turnover and myocardial contractility. Our study aimed to identify the relationship between vitamin D deficiency and myocardial function (both systolic and diastolic) in medical staff with an adverse history of cardiac disease and normal transthoracic echo Doppler parameters. Methods: A comparative cross-sectional study involved 80 doctors, nurses, and technicians working at Zagazig University Hospitals; they were divided into two groups based on 25(OH) D levels: Group A (n=40) had a low vitamin D level of <20 ng/mL & Group B (n=40) had an average vitamin D level (>20 ng/ml). Both groups were subjected to conventional echocardiography and tissue Doppler imaging. Results:The study found significantly higher Left ventricular and right ventricular Tei index in group A compared to group B (P value =0.01 and ˂0.001), respectively We also found a significantly higher tricuspid deceleration time (DT (t)), tricuspid lateral A' and significantly longer tricuspid interventricular isovolumetric relaxation time (IVRT(T) in group A compared to group B. Finally, a receiver operating characteristic (ROC) c urve was performed which showed that 25(OH) D less than 19.5 was found to have 83% sensitivity and 65% specificity in determining a high RV tei index (>0.55).Conclusions: Our study showed that Vitamin D deficiency affects both the systolic and diastolic function of the heart. Keywords: Vitamin D, Cardiac function, Tissue Doppler imaging, TEI index
Author Related Publications
Moataz Abdel Moneim Mohammed Qott, "The Role of the Platelet/Lymphocyte Ratio and Neutrophil/Lymphocyte Ratio in Predicting High-Risk Heart Score in Patients Admitted with Non-ST Elevation Acute Coronary Syndrome", pulse, 2020
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Moataz Abdel Moneim Mohammed Qott, "Global Left Ventricular Function Index as a Predictor of Subclinical Contractile Dysfunction in Patients with Concentric Left Ventricular Hypertrophy", zagazig university medical journal, 2023
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Moataz Abdel Moneim Mohammed Qott, "Validity of the Triglyceride–Glucose Indices for Predicting the Severity of Coronary Artery Disease in Patients With Nondiabetic Chronic Coronary Syndrome", Critical Pathwaya in Cardiology, 2024
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Moataz Abdel Moneim Mohammed Qott, "Prediction of Embolic Stroke in Non-Valvular Atrial Fibrillation Patients with Low CHADS-VASc Score", zagazig university medical journal, 2024
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Alaa Alsayed Mohamed Abdallah Salama, "VALUE OF THE ELECTROCARDIOGRAPHIC STRAIN PATTERN IN CHILDREN AND ADOLESCENTS WITH END STAGE RENAL DISEASE", المجلة الطبية لجامعة القاهرة, 2015
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Abdelhakim Selem Elsayed Sliem, "CLINICAL STUDIES Quantification of Left Ventricular Function with Contrast-Enhanced Harmonic Colour Doppler and a Semiautomated Boundary Detection Algorithm in Technically Difficult Patients: Feasibility, Accuracy, and Inter-observer V", The European Society of Cardiology, 2001
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