Metabolite Profiling of Date Palm Fruit (Phoenix dactylifera L.) And Its Cytoprotective Effects Versus Vitamin C Against Mobile Phone Radiation- Induced Adrenal Gland Damage In Rats

Faculty Medicine Year: 2024
Type of Publication: ZU Hosted Pages:
Authors:
Journal: zagazig medical journal zagazig medical journal Volume:
Keywords : Metabolite Profiling , Date Palm Fruit (Phoenix    
Abstract:
Date palm fruit (Phoenix dactylifera L.) can be used as a pharmaceutical product because of its rich phytochemical composition. Mobile phone radiation is a type of electromagnetic radiation (EMR) that has been confirmed to exert several adverse effects on living tissues. Methods: In this study, we investigated the phytochemicals of the Egyptian date palm fruit using ultra-performance liquid chromatography with electrospray ionization quadrupole- linear ion trap tandem mass spectrometry analysis (UPLC-ESI-MS/MS) in negative and positive ionization modes. Adult male Wister albino rats were exposed to mobile phone induced electromagnetic radiations (EMR) for 1 hour per day for 4 weeks. We evaluated the possible cytoprotective effects of date palm fruits compared with vitamin C on mobile phone induced EMR. Rats were divided into the control, EMR, and two EMR groups treated with either vitamin C or date palm fruit.
   
     
 
       

Author Related Publications

  • Sahar Kamal Younis Aly, "Ellagic acid protects against gastric ulcer in male rats by antioxidant and anti-inflammatory mechanisms: modulation of NF-κβ/COX-2 and Nrf2/HO-1 pathways", taylor & francis, 2025 More
  • Sahar Kamal Younis Aly, "Dihydroartemisinin attenuates acetic acid-induced ulcerative colitis in rats: Suppression of inflammation and modulation of NFκβ/TNF-α/ RIPK1-mediated necroptosis and apoptosis", Elsevier Ltd, 2025 More
  • Sahar Kamal Younis Aly, "Harnessing Nature for Breast Cancer Management: Effects of Fisetin-Loaded Nigellasomes Embedded in Microneedles Improve Tumor Suppression and Reduce Oxidative Stress", MDPI, 2025 More
  • Sahar Kamal Younis Aly, "Harnessing Dual Power: Genistein-Loaded Pumpkisomes in Pullulan Microneedles for Potent Antioxidant and Anticancer Therapy Against Ehrlich Ascites Carcinoma and Breast Cancer Cells", MDPI, 2025 More
  • Sahar Kamal Younis Aly, "Human Wharton’s jelly-derived mesenchymal stromal stem cells preconditioned with valproic acid promote cell migration and reduce renal inflammation in ischemia/reperfusion injury by activating the AKT/P13K and SDF1/CXCR4 pathways", ELSEVIER, 2024 More

Department Related Publications

  • Rasha Mohamed Sabry, "Efficacy of olibanum and propolis medicinal extracts versus metronidazole in Giardia lamblia experimentally infected mice", zagazig university, 2020 More
  • Rasha Mohamed Sabry, "Protective Effect of Date Palm Fruits (Phoenix Dactylifera L.) versus Vitamin C Against Mobile Phone Radiation-induced Pituitary Gland Damage in Rats", Zagazig University, 2022 More
  • Rasha Mohamed Sabry, "Mitigation of dexamethasone-induced nephrotoxicity by modulating the activity of adrenergic receptors: Implication of Wnt/β-arrestin2/ β-catenin pathway", elsevier, 2022 More
  • Rasha Mohamed Sabry, "Metabolite Profiling of Date Palm Fruit (Phoenix dactylifera L.) And Its Cytoprotective Effects Versus Vitamin C Against Mobile Phone Radiation-Induced Adrenal Gland Damage In Rats", zagazig university, 2022 More
  • Rasha Mohamed Sabry, "Amlexanox Exhibits Cardioprotective Effects in 5/6 Nephrectomized Rats", -scielo, 2021 More
Tweet