Around the world, heavy metal pollution is viewed as a serious issue. The main ways that heavy metals enter the human body are through food, drink, and air. Although a significant source of animal-derived protein, vitamins, and trace minerals, shellfish can also be a source of human exposure to heavy metals. The seasonal impact on the heavy metal load in shellfish had received less attention. The goal of this study was to track the levels of the toxic metal residues, lead (Pb), cadmium (Cd), mercury (Hg), and arsenic (As), in the edible parts of the crab and shrimp collected nearby the red sea shores in Suez city, Egypt. Additionally, estimated daily intakes, and a risk assessment for human health were calculated. This study showed that the edible tissues of shrimp and crab samples taken from Egypt contained the hazardous metals Pb, Cd, As, and Hg. When compared to shrimp, crab in particular showed higher quantities of these components. When comparing samples obtained in the winter to those collected in the summer, the heavy metal burden in the investigated samples was significantly higher in the winter samples. The Egyptian populace may have been exposed to dangers related to toxic metals when the potential health risks linked with consuming such shellfish were calculated. Consequently, it is best to limit your daily intake of crab and shrimp, especially during the winter.