The field experiment was conducted in a Private Farm at Qutaiyifet ElAziziya Village, Minya El-Qamh District, Sharkia Governorate, Egypt, in a split-plot design with three replications during the two successive winter seasons of 2021/2022 and 2022/2023. This investigation aimed to find out the effect of nitrogen fertilizer levels under some new technological fertilizer (Compound fertilizer in liquid form, bio – fertilizers and Nano-fertilizer) on wheat (Misr-1 cv.) growth, yield and its components. The main plots allotted to liquid compound fertilizer (1L /fed), commercial bio-fertilizers (at the rate of 1 kg /fed from Cerialine, Phosphourine and Potassiummag) and N, P, K Nano-fertilizer (400-ppm /fed). While sub plots assigned to five mineral N- fertilizer rates (0.0, 40, 60, 80 and 100 kg /fed) as ammonium nitrate. The important results could be summarized as follows: 1- Liquid compound fertilizer (as new technological fertilizer) led to higher values of plant height (cm), number of green leaves, flag leaf area (cm2), No. of grains/spike, No. of spikelets / spike, 1000- grain weight, biological yield (ton /fed), as well as harvest index (%). 2- Nitrogen fertilization with rate of 100 kg /fed has been resulted in better biological yield (ton /fed), harvest index (%) and 1000- grain weight beside higher values of plant height, number of green leaves, No. of grains/spike, No. of spikelets / spike, flag leaf area (cm2). 3- The interaction treatment of (100 kg N /fed + liquid compound fertilizer 1L /fed) in the two-studied successive growth growing seasons was the best one, which recorded the maximum values for the previous studied parameters. Conclusively: it could be concluded that the use of 100 kg N /fed., with technological fertilizers (compound fertilizer in the liquid form) under clayey soil conditions gave the highest value of wheat production (Misr-1 cv.) at Sharkia Governorate conditions, Egypt.