The current research aimed to test the impact of managerial entrenchment mechanisms on the cost of capital, as managerial entrenchment mechanisms were measured through (CEO duality, CEO tenure, board independence, managerial ownership, and financial leverage), and the cost of capital measured by the weighted average cost of capital, by answering the following question: Do managerial entrenchment mechanisms affect the cost of capital? In order to test the research hypotheses, 75 Egyptian Listed Companies were used during the period from 2015-2018, the results indicate: - There is a negative association between CEO duality and the cost of capital, and there is also negative association between managerial ownership and the cost of capital, as well as there is a positive association between financial leverage and the cost of capital. - The relationship between CEO tenure and the cost of capital was not significant, as well as the relationship between the board independence and the cost of capital was not significant. Which confirms the important role that managerial entrenchment mechanisms can play, especially (CEO duality, managerial ownership, and financial leverage), in determining the cost of capital.