The detrimental effects of drought have adverse impacts on the crop yield as global climatic changes put unusual pressure on water resources. The challenge of attaining water security is key for the sustainable development of crops. Zinc (Zn 2+) is an important nutrient that helps to alleviate drought stress by modulating the growth and yield of crops. Recently, zinc nanoparticles (ZnNPs) have been used as a novel strategy for the fertilization of crops. This study was specifically developed to observe the comparative effects of ZnNPs and conventional zinc sulfate (ZnSO 4) at diverse concentration levels (0.01%, 0.05%, and 0.1%) that could effectively decrease the injurious effect of drought stress on turnip plants. In experiments on the golden turnip variety, drought stress caused a significant reduction in all growth and biochemical attributes, and increased antioxidant enzymatic activity. In a comparison with the conventional fertilizer ZnSO 4 , the foliar application of 0.1% ZnNPs significantly improved plant height, biomass, root/turnip length, turnip diameter, antioxidant defense system, secondary metabolites, and photosynthetic pigments in the leaves under drought stress. Based on the collected results, it is suggested that the foliar application of ZnNPs, instead of ZnSO 4, under drought stress is helpful in increasing the growth and yield of turnip plants