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Design and Synthesis of a Novel ICT Bichromophoric pH Sensing System Based on 1,8-Naphthalimide Fluorophores as a Two-Input Logic Gate and Its Antibacterial Evaluation
Faculty
Science
Year:
2024
Type of Publication:
ZU Hosted
Pages:
15
Authors:
Alaa Rasheed Helmy Rashid Saqr
Staff Zu Site
Abstract In Staff Site
Journal:
MOLECULES MDPI
Volume:
28
Keywords :
Design , Synthesis , , Novel , Bichromophoric , Sensing System
Abstract:
The synthesis, sensor activity, and logic behavior of a novel 4-iminoamido-1,8-naphthalimide bichromophoric system based on a “fluorophore-receptor” architecture with ICT chemosensing properties is reported. The synthesized compound showed good colorimetric and fluorescence signaling properties as a function of pH and proved itself as a promising probe for the rapid detection of pH in an aqueous solution and base vapors in a solid state. The novel dyad is able to work as a two-input logic gate with chemical inputs H+ (Input 1) and HO− (Input 2) executing INHIBIT logic gate. The synthesized bichromophoric system and the corresponding intermediates demonstrated good antibacterial activity toward Gram (+) and Gram (−) bacteria when compared with the Gentamycin standard. Keywords: 1,8-naphthalimide; ICT bichromophore; pH sensing; strip paper indicator; INHIBIT and IMPLICATION logic gates; fluorescence; antibacterial activity
Author Related Publications
Alaa Rasheed Helmy Rashid Saqr, "Design and chemical behavior of novel pyrimidine derivatives and their evaluation of cytotoxicity", Taylor and Francis Group, 2020
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Alaa Rasheed Helmy Rashid Saqr, "Design and synthesis of novel fluorescence sensing perylene diimides based on photoinduced electron transfer", Elsevier, 2011
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Alaa Rasheed Helmy Rashid Saqr, "Design and chemical behavior of novel pyrimidine derivatives and their evaluation of cytotoxicity", Springer, 2020
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Department Related Publications
Fathi Ahmed Abdul Latif Yassin, "Pyridazine Derivatives and Related Compounds, Part 4(1): pyrrolo and furo pyridazines : sy pnthesis and reactions", ألمانيا, 1992
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Fathi Ahmed Abdul Latif Yassin, "Synthesis and antimicrobial activity of some new triazino , triazolo and pyrazolo pyridazine derivatives", الهند, 2008
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Fathi Ahmed Abdul Latif Yassin, "Pyridazin And Its Related Compounds Part 25 : Synthesis Of New Arylazopyrazolthieno[2,3-c]-Pyridazine Type Dispersion Dyes", انجلترا, 2014
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Ayman AboulFotouh Gouda Sallem, "Design and utilisation of a novel poly imino-phosphorane composite for the effective removal of Pb2+ and Cr3+ ions from contaminated water sources", Taylor & Francis, 2024
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Fathi Ahmed Abdul Latif Yassin, "Synthesis and Characterization of some Disperse Dyes based on Enaminones Synthesis and Characterization of some Disperse Dyes based on Enaminones", Springer, 2020
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