High-temperature resistant material is becoming increasingly significant in numerous industrial applications, including aerospace and automotive use, to increase fuel efficiency and decrease CO2 emissions. Metals with nanoparticles to form metal matrix nano composite (MMNCs) are promising to enhance metals for structural/industrial applications at high temperatures. This review provides a comprehensive insight into the nanoparticle effect on the creep behavior of metals and alloys. Firstly, it discusses the different creep mechanisms that are activated in response to the creep strain according to the deformation parameters (temperature, load, and microstructure). The most significant creep mechanisms vary according to the grain shape accommodation mechanism required to facilitate the grain boundary sliding into accommodation by diffusion and accommodation by intragranular dislocation activity. Secondly, it reviews the threshold stress contribution in metal matrix composites as well as the load transfer phenomenon, which enhances creep resistance of metals with nanoparticles. Thirdly, the nanoparticles' influences on the creep behavior of metals, especially Al, Mg, Ti, Zn, and solder alloys, are reviewed in detail. Finally, a summary of this review and the future aspects associated with the behavior of metals with nanoparticles at high temperatures are provided.