The fluid flow through blunt bodies that are yawed and un-yawed frequently happens in many engineering applications. The practical significance of deep-water applications such as propagation control, splitting the boundary layer over submerged blocks, and preventing recirculation bubbles is explained by the fluid flow across a yawed cylinder. The current work examined the mixed convective flow and convective heat transfer by incorporating water-based graphene oxide nanofluid around a yawed cylinder with viscous dissipation and irregular heat source/sink. To investigate the heat diffusion across the system of buoyancy effects, the mathematical formulation of the problem was modeled in terms of coupled, nonlinear partial differential equations. The boundary value problem of the fourth-order (bvp4c) solver was operated to find the non-similarity solution. The outcomes indicated that the velocity in both directions enlarged owing to the higher impacts of yaw angle for the phenomenon of assisting flow but decreased for the instance of opposing flow, while the temperature of nanofluid increased because of heightened estimations of yaw angle for both assisting and opposing flows. In addition, with larger impacts of nanoparticle volume fraction, the shear stresses were enhanced by about 0.76% and 0.93% for the case of assisting flow, while for the case of opposing flow, they improved by almost 0.65% and 1.38%, respectively.