In vivo investigation of the anti-liver fibrosis impact of Balanites aegyptiaca chitosan nanoparticles

Faculty Veterinary Medicine Year: 2024
Type of Publication: ZU Hosted Pages: 116193
Authors:
Sherif Khayry Abdelmoeti Mohamed
Journal: Biomedicine & Pharmacotherapy Elsevier Masson SAS Volume: 172
Keywords : , vivo investigation , , anti-liver fibrosis impact , Balanites    
Abstract:
The current study used the ionotropic gelation process to effectively establish B. aegyptiaca/chitosan nanoparticles. Formula features have been displayed. The obtained B. aegyptiaca/chitosan nanoparticles demonstrated greater effectiveness towards CCl4 toxicity-induced liver fibrosis by diminishing histological variations and liver functions, as well as regulating oxidative markers, which may be caused by targeting gene expression for specific genes controlling fibrosis and minimizing α- SMA area, according to the in vivo results.
    
     
 
       

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