STING activator 2′3′-cGAMP enhanced HSV-1-based oncolytic viral therapy

Faculty Veterinary Medicine Year: 2024
Type of Publication: ZU Hosted Pages: 1-19
Authors:
Mohamed Abdel Moneim Ahmed Ali Mohamed
Journal: Molecular Oncology Wiley Volume: 18
Keywords : STING activator 2′3′-cGAMP enhanced HSV-1-based oncolytic    
Abstract:
Oncolytic viruses (OVs) can selectively replicate in tumor cells and remodel the microenvironment of immunologically cold tumors, making them a promising strategy to evoke antitumor immunity. Similarly, agonists of the stimulator of interfe
    
     
 
       

Author Related Publications

  • Mohamed Abdel Moneim Ahmed Ali Mohamed, "Metformin enhances the antitumor activity of oncolytic herpes simplex virus HF10 (canerpaturev) in a pancreatic cell cancer subcutaneous model", Springer Nature, 2022 More
  • Mohamed Abdel Moneim Ahmed Ali Mohamed, "Anti-Inflammatory and Immunomodulatory Role of Bone Marrow-Derived MSCs in Mice with Acute Lung Injury", Mary Ann Liebert, Inc., 2021 More
  • Mohamed Abdel Moneim Ahmed Ali Mohamed, "Oncolytic herpes simplex virus HF10 (canerpaturev) promotes accumulation of CD8+PD-1− tumor-infiltrating T cells in PD-L1-enriched tumor microenvironment", wiley online library, 2021 More
  • Mohamed Abdel Moneim Ahmed Ali Mohamed, "C-REV Retains High Infectivity Regardless of the Expression Levels of cGAS and STING in Cultured Pancreatic Cancer Cells", MDPI, 2021 More
  • Mohamed Abdel Moneim Ahmed Ali Mohamed, "S-1 facilitates canerpaturev (C-REV)-induced antitumor efficacy in a triple-negative breast cancer model", Nagoya University School of Medicine/Graduate School of Medicine, 2021 More

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