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Progression From Paroxysmal to Persistent Atrial Fibrillation. Clinical Correlates and Prognosis
Faculty
Medicine
Year:
2010
Type of Publication:
ZU Hosted
Pages:
725-731
Authors:
Aly Mohamed Abdelrahman Saad
Staff Zu Site
Abstract In Staff Site
Journal:
Journal Of American College Of Cardiology American College Of Cardiology Foundation
Volume:
Keywords :
Progression From Paroxysmal , Persistent Atrial Fibrillation.
Abstract:
Objectives We investigated clinical correlates of atrial fibrillation (AF) progression and evaluated the prognosis of patients demonstrating AF progression in a large population. Background Progression of paroxysmal AF to more sustained forms is frequently seen. However, not all patients will progress to persistent AF. Methods We included 1,219 patients with paroxysmal AF who participated in the Euro Heart Survey on AF and had a known rhythm status at follow-up. Patients who experienced AF progression after 1 year of follow-up were identified. Results Progression of AF occurred in 178 (15%) patients. Multivariate analysis showed that heart failure, age, previous transient ischemic attack or stroke, chronic obstructive pulmonary disease, and hypertension were the only independent predictors of AF progression. Using the regression coefficient as a benchmark, we calculated the HATCH score. Nearly 50% of the patients with a HATCH score> 5 progressed to persistent AF compared with only 6% of the patients with a HATCH score of 0. During follow-up, patients with AF progression were more often admitted to the hospital and had more major adverse cardiovascular events. Conclusions A substantial number of patients progress to sustained AF within 1 year. The clinical outcome of these patients regarding hospital admissions and major adverse cardiovascular events was worse compared with patients demonstrating no AF progression. Factors known to cause atrial structural remodeling (age and underlying heart disease) were independent predictors of AF progression. The HATCH score may help to identify patients who are likely to progress …
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Aly Mohamed Abdelrahman Saad, "The prevalence of abnormal glucose regulation in patients with coronary artery disease across Europe The Euro Heart Survey on diabetes and the heart", Elsevier, 2004
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Aly Mohamed Abdelrahman Saad, "Treatment and Health Status in Patients with Proven Coronary Artery Disease, but Ineligible for Revascularization. A Report from the Euro Heart Survey on Revascularization", Sage, 2006
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Aly Mohamed Abdelrahman Saad, "Pharmacological treatment and perceived health status during 1-year follow up in patients diagnosed with coronary artery disease, but ineligible for revascularization: Results from the Euro Heart Survey on coronary revascularization", Sage, 2006
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Aly Mohamed Abdelrahman Saad, "A 1-year follow up in patients diagnosed with coronary artery disease, but ineligible for revascularization. Results from The Euro Heart Survey on Coronary Revascularization", Oxford University Press, 2006
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Aly Mohamed Abdelrahman Saad, "Atrial fibrillation management: a prospective survey in ESC Member Countries", Oxford University Press, 2005
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Department Related Publications
Khaled Mohamed Abdelsalam, "تقييم وظيفة البطين الايسر بعد العلاج الشرايين التاجيةبالقسطرة التداخلية", لايوجد, 1900
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Muntasir Mustafa Ahmad, "هل يوجد دور للاعتلال وظائف البطانة الوعائية في عودة ضيق الشريان", لايوجد, 1900
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Mohammed Hossam El Din Mohamed Shaer, "انماط سرعة تدفق الدم في الشريان التاجى فى ارتجاع الصمام الاورطي المزمن دراسة بالموجات فوق الصوتية خلال محبس المرى", مجلة جامعة الزقازيق الطبية, 2000
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Ahmed Shafea Mahmoud Morsy, "مستوي الاديبونكتين في بلزما دم مرضي الشريان التاجي", مجلة جامعة الزقازيق الطبية, 2001
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Mohamed Ibrahim Mustafa AlAwadi, "الموجودات بالمنظار بين مرضى الشريان التاجى وهيلكوباكتر بيلورى السيرو الموجب عامل خطورة جديد", مجلة جامعة الزقازيق الطبية, 1998
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