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Acute Coronary Syndrome and Ischemic Heart Disease in Pregnancy: Data From the EURObservational Research Programme‐European Society of Cardiology Registry of Pregnancy and Cardiac Disease
Faculty
Medicine
Year:
2020
Type of Publication:
ZU Hosted
Pages:
Authors:
Aly Mohamed Abdelrahman Saad
Staff Zu Site
Abstract In Staff Site
Journal:
Journal of the American Heart Association Journal of the American Heart Association
Volume:
Keywords :
Acute Coronary Syndrome , Ischemic Heart Disease
Abstract:
Abstract Background The prevalence of ischemic heart disease (IHD) in women of child‐bearing age is rising. Data on pregnancies however are scarce. The objective is to describe the pregnancy outcomes in these women. Methods and Results The European Society of Cardiology‐EURObservational Research Programme ROPAC (Registry of Pregnancy and Cardiac Disease) is a prospective registry in which data on pregnancies in women with heart disease were collected from 138 centers in 53 countries. Pregnant women with preexistent and pregnancy‐onset IHD were included. Primary end point were maternal cardiac events. Secondary end points were obstetric and fetal complications. There were 117 women with IHD, of which 104 had preexisting IHD. Median age was 35.5 years and 17.1% of women were smoking. There was no maternal mortality, heart failure occurred in 5 pregnancies (4.8%). Of the 104 women with preexisting IHD, 11 women suffered from acute coronary syndrome during pregnancy. ST‐segment‒elevation myocardial infarction were more common than non‒ST‐segment‒elevation myocardial infarction, and atherosclerosis was the most common etiology. Women who had undergone revascularization before pregnancy did not have less events than women who had not. There were 13 women with pregnancy‐onset IHD, in whom non‒ST‐segment‒elevation myocardial infarction was the most common. Smoking during pregnancy was associated with acute coronary syndrome. Caesarean section was the primary mode of delivery (55.8% in preexisting IHD, 84.6% in pregnancy‐onset IHD) and there were high rates of preterm births (20.2% and 38.5%, respectively). Conclusions Women with IHD tolerate pregnancy relatively well, however there is a high rate of ischemic events and these women should therefore be considered moderate‐ to high‐risk. Ongoing cigarette smoking is associated with acute coronary syndrome during pregnancy.
Author Related Publications
Aly Mohamed Abdelrahman Saad, "The prevalence of abnormal glucose regulation in patients with coronary artery disease across Europe The Euro Heart Survey on diabetes and the heart", Elsevier, 2004
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Aly Mohamed Abdelrahman Saad, "Treatment and Health Status in Patients with Proven Coronary Artery Disease, but Ineligible for Revascularization. A Report from the Euro Heart Survey on Revascularization", Sage, 2006
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Aly Mohamed Abdelrahman Saad, "Pharmacological treatment and perceived health status during 1-year follow up in patients diagnosed with coronary artery disease, but ineligible for revascularization: Results from the Euro Heart Survey on coronary revascularization", Sage, 2006
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Aly Mohamed Abdelrahman Saad, "A 1-year follow up in patients diagnosed with coronary artery disease, but ineligible for revascularization. Results from The Euro Heart Survey on Coronary Revascularization", Oxford University Press, 2006
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Aly Mohamed Abdelrahman Saad, "Atrial fibrillation management: a prospective survey in ESC Member Countries", Oxford University Press, 2005
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Department Related Publications
Ahmed Shafea Mahmoud Morsy, "قيمه سمك الطانه والطبقة الوسطي للشريان السباتي والفخذي كعامل غير نافذ للتنبؤ بمرض الشريان التاجي", مجلة القلب المصرية, 2001
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Ahmed Shafea Mahmoud Morsy, "تاثير توسيع الصمام الميترالي بالقسطره البالونية علي الارتجاع الوظيفي للصمام ثلاثي الشرفات وارتفاع ضغط الشريان الرئوي", مجلة جامعة الزقازيق الطبية, 2000
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Tarek Abdelmoniem Abdelaziz, "Human C-reactive protein gene polymorphism andmetabolic syndrome are associated with premature coronary artery disease", Elsevier, 2013
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Tarek Abdelmoniem Abdelaziz, "Synergistic Effect Between Lipoprotein Lipase and Apolipoprotein C3 Genes in Determining the Severity of Coronary Artery Disease", Springer, 2013
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Eslam Alsayed Mohamed Mohamed Shehata, "Mitral annulus time intervals for assessment of left ventricular systolic function in ischemic cardiomyopathy", European Journal of Heart Failure Supplements (2012) 11, S128–S177, 2012
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