Zagazig University Digital Repository
Home
Thesis & Publications
All Contents
Publications
Thesis
Graduation Projects
Research Area
Research Area Reports
Search by Research Area
Universities Thesis
ACADEMIC Links
ACADEMIC RESEARCH
Zagazig University Authors
Africa Research Statistics
Google Scholar
Research Gate
Researcher ID
CrossRef
Risk of Pregnancy in Moderate and Severe Aortic Stenosis: From the Multinational ROPAC Registry
Faculty
Medicine
Year:
2016
Type of Publication:
ZU Hosted
Pages:
1727-1737
Authors:
Aly Mohamed Abdelrahman Saad
Staff Zu Site
Abstract In Staff Site
Journal:
Journal of the American College of Cardiology American College Of Cardiology Foundation
Volume:
16
Keywords :
Risk , Pregnancy , Moderate , Severe Aortic Stenosis: From , Multinational
Abstract:
Abstract Background: Controversial results on maternal risk and fetal outcome have been reported in women with aortic stenosis (AS). Objectives: The authors sought to investigate maternal and fetal outcomes in patients with AS in a large cohort. Methods: The Registry on Pregnancy and Cardiac Disease (ROPAC) is a global, prospective observational registry of women with structural heart disease, providing a uniquely large study population. Data of women with moderate (peak gradient 36 to 63 mm Hg) and severe AS (peak gradient ≥64 mm Hg) were analyzed. Results: Of 2,966 pregnancies in ROPAC, the authors identified 96 women who had at least moderate AS (34 with severe AS). No deaths were observed during pregnancy and in the first week after delivery. However, 20.8% of women were hospitalized for cardiac reasons during pregnancy. This was significantly more common in severe AS compared with moderate AS (35.3% vs. 12.9%; p = 0.02), and reached the highest rate (42.1%) in severe, symptomatic AS. Pregnancy was complicated by heart failure in 6.7% of asymptomatic and 26.3% of symptomatic patients, but could be managed medically, except for 1 patient who was symptomatic before pregnancy and underwent balloon valvotomy. Children of patients with severe AS had a significantly higher percentage of low birth weight (35.0% vs. 6.0%; p = 0.006). Conclusions: Mortality in pregnant women with AS, including those with severe AS, appears to be close to zero in the current era. Symptomatic and severe AS does, however, carry a substantial risk of heart failure and is associated with high rates of hospitalization for cardiac reasons, although heart failure can nearly always be managed medically. The results highlight the importance of appropriate pre-conceptional patient evaluation and counseling.
Author Related Publications
Aly Mohamed Abdelrahman Saad, "The prevalence of abnormal glucose regulation in patients with coronary artery disease across Europe The Euro Heart Survey on diabetes and the heart", Elsevier, 2004
More
Aly Mohamed Abdelrahman Saad, "Treatment and Health Status in Patients with Proven Coronary Artery Disease, but Ineligible for Revascularization. A Report from the Euro Heart Survey on Revascularization", Sage, 2006
More
Aly Mohamed Abdelrahman Saad, "Pharmacological treatment and perceived health status during 1-year follow up in patients diagnosed with coronary artery disease, but ineligible for revascularization: Results from the Euro Heart Survey on coronary revascularization", Sage, 2006
More
Aly Mohamed Abdelrahman Saad, "A 1-year follow up in patients diagnosed with coronary artery disease, but ineligible for revascularization. Results from The Euro Heart Survey on Coronary Revascularization", Oxford University Press, 2006
More
Aly Mohamed Abdelrahman Saad, "Atrial fibrillation management: a prospective survey in ESC Member Countries", Oxford University Press, 2005
More
Department Related Publications
Mohammed Wafaay Moursy AboulEinein , "دراسة كتلة البطين الايسر باستخدام الفحص بالرنين المغناطيسى بالمقارنة بنتائج الفحوص الاخرى", لايوجد, 1900
More
Mohammed Hossam El Din Mohamed Shaer, "مجال الانبساط للبطين الايسر المتضخم تاثير المسبب ومرض الشريان التاجي على سرعات الدوبلر عبر الصمام الميترالى", مجلة جامعة الزقازيق الطبية, 1997
More
Mohammed Hossam El Din Mohamed Shaer, "العلاقة بين الاداء الانبساطي للبطين الايسر وقدرة تحمل القلب للمجهود ومدي اصابة الشريان التاجى الغير مرتبط بالاحتشاء", مجلة جامعة الزقازيق الطبية, 1999
More
Mohamed Ibrahim Mustafa AlAwadi, "مقارنة طريقة منطقة التقاء التدفق بالطرق التقليدية باستخدام الموجات الفوق صوتية للقلب مساحة الصمام الميترالى فى حالات ضيق الصمام الميترالى", مجلة جامعة الزقازيق الطبية, 2000
More
Tarek Abdelmoniem Abdelaziz, "Association of endothelial nitric oxide synthase gene polymorphisms with classical risk factors in development of premature coronary artery disease", 3, 2013
More
جامعة المنصورة
جامعة الاسكندرية
جامعة القاهرة
جامعة سوهاج
جامعة الفيوم
جامعة بنها
جامعة دمياط
جامعة بورسعيد
جامعة حلوان
جامعة السويس
شراقوة
جامعة المنيا
جامعة دمنهور
جامعة المنوفية
جامعة أسوان
جامعة جنوب الوادى
جامعة قناة السويس
جامعة عين شمس
جامعة أسيوط
جامعة كفر الشيخ
جامعة السادات
جامعة طنطا
جامعة بنى سويف