Pots experiment was designed in two summer successive seasons of 2017 and 2018 at the wire house of the Agric. Bot. Dept., Fac. Agric. Zagazig Univ., Sharkia Governorate, Egypt. Common bean plants cv. Giza 3 were foliar sprayed with different concentrations of humic acid, proline, naphthalene acetic acid and distilled water (as a control) under sea water salinity levels, i.e. 1000, 2000 and 3000 ppm and tap water (500 ppm) as a control, to examine its effects on growth, photosynthetic pigments, proline content, yield and leaf anatomy of common bean plants. Results revealed that most studied traits, i.e., plant height, number of leaves/plant, leaf area, fresh weight of roots, stems and leaves, photosynthetic pigments (chlorophyll a, chlorophyll b, chlorophyll a+b and carotenoids) and yield expressed as number of pods/plant, number of seeds/pod, number of seeds/ plant, 100-seed weight and length of pod as well as leaf anatomical parameters. Most aforementioned features were significantly decreased with increasing sea water levels up to the highest level (3000 ppm) comparison with control (tap water). On the contrary, proline content in leaves was increased with increasing salinity levels up to 3000 ppm. On the other hand, spraying common bean plants with humic acid at 2 and 4g/L, proline at 50 and 100 ppm and naphthalene acetic acid at 25 and 50 ppm had a positive significant effect in most studied traits compared to control (distilled water). In general, the most favorable treatments were foliar spray common bean plants with humic acid at 2g/L followed by proline at 100 ppm then naphthalene acetic acid at 25 ppm, respectively compared to control (distilled water). It could be concluded that spraying of humic acid, proline and naphthalene acetic acid mitigate the harmful effect of sea water salinity on common bean plants and the best treatment was interaction between irrigation with tap water or sea water at 1000 ppm and spraying by humic acid at 2 g/L.