The Computer Vision Syndrome (CVS) related to the usage of computers has been duetolow compliance with ergonomic features. The aim of that research was to assess theeffectiveness of educational intervention about computer vision syndrome on the severityof eye complaints among computer users. Design: A quasi-experimental interventional studywith pre-post evaluation was performed. Setting: The research was concluded intheadministrative buildings of Zagazig University/Egypt. Subjects: Seventy-five computer operators were included in the current study. Tools: Three questionnaires were used for datagathering, which includes I. computer user's self-administered questionnaire, and Selfreported eye complaints' and computer users' CVS knowledge scale, II. Observationandmeasurement of the employees' computer ergonomic practices, and III. Assessment of thecomputer workstation design. Results: Following educational intervention by 1 and3months, the total-eye-complaints score, total-knowledge score, and the total protectiveergonomic practices scores showed a statistically significant difference. Additionally, after one and three months, the overall workstation score showed a substantial mean difference. Conclusion: As a result of the educational intervention regarding computer vision syndromeand its preventive ergonomic practices, computer users' observed eye symptoms decreased, their knowledge about computer vision syndrome improved. Their protective ergonomicpractices and workstation proposal were remodeled. Recommendation: Based on the studyfindings, it is recommended that application the educational intervention about theergonomic training program Computer operating employees, and acquiescence torecommend office ergonomics are essential to alleviate the growing prevalence in CVScases. Keywords: Computer Vision Syndrome, Eye Complaints, Education Intervention, Knowledge, Ergonomic Practices, Computer Users, Workstation Design