Green micellar liquid chromatographic analysis of alfuzosin hydrochloride and sildenafil citrate in a binary mixture compared to classical RPLC with stability indicating studies

Faculty Pharmacy Year: 2022
Type of Publication: ZU Hosted Pages:
Authors:
Journal: Drug Development and Industrial Pharmacy Taylor & Francis Volume:
Keywords : Green micellar liquid chromatographic analysis , alfuzosin    
Abstract:
تعيين مخلوط مادتى ألفوزوسين هيدروكلوريد و سيلدينافيل سترات باستخدام كروماتوجرافيا السائل ذات الكفاءة العالية و استخدام أطوار متحركة تقليدية و اخرى صديقه للبيئة كالمحاليل الغروية (الكيمياء الخضراء) مع الاظهار الطيفى عند طول موجى 225 نانومتر. و قد امكن تعيين كلا من المركبين فى خليط من صورتهما النقية و المستحضرات الصيدلية و كذلك تم قياس الثباتية للمركبات محل الدراسة بعد تعرضهم لظروف تكسير مختلفة. وقد تمت مقارنة نتائج الطريقتين إحصائيا بالنتائج الدستورية و المرجعية التى جاءت متفقه معها.
   
     
 
       

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